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Myelofibrosis Sample
   
Myelofibrosis 40x
   
Myelofibrosis 200x
   

Myelofibrosis (myelofibrosis)

The sample is a piece of bone marrow, with increased fibrosis. In the acute phase hyperplasia of all myeloid cell-lines (erythroblasts, megakaryocytes and granulocytes) is found. In places megakaryocytes are found in groups (arrows). With reticulin-staining, the increase of reticulin-fibers can be pin-pointed. There is also adipose tissue in bone marrow. 40x magnification, HE-staining.